I can't vouch for those two, but I have two Liberty cans plus and integral and all three have very discernable differences for a .22 can. IMO/E, there's a lot more difference between .22 cans than there is the larger ones. The Liberty Regulator is the most quiet can I've ever used and it's super simple too (they admitted to hitting on it by accident too just fucking around). Almost too simple to work. The Essence cost twice as much, weighs 1oz. or so less but has more noticeable FRP and is a bit louder; cost is probably due to Ti core, more machining steps, more complicated build. The Regulator is quiet enough that I mostly use it on a PPK/S simply because the action is quieter and that's what's making all the noise with this can. 1cc of water and it's basically silent, just the clacking of the action.
The integral Pinnacle 2 is by far the most quiet with basically no FRP (also a Liberty --I just like them for .22 stuff, most of my other stuff is TBAC, Sico, Elite, etc.). It also went into a Kidd action and Titan stock so it's also the best 10/22 I've ever used. Snapping fingers quiet.
Most .22 cans use similar baffle stacks from what I've seen. The Liberty cans are monocore. This is nice because the core is what is threaded and in a takedown can, wear and tear can end up causing the baffles to go back in out of line (some have a sleeved core because of this, to prevent it, I think the Sico has that, not sure). That's the major difference between Liberty cans and others in general. I'm not a big fan of their larger cans, I have a Mystic X and it's fine really, but I swear by their .22 stuff.
You definitely want it takedown, and I'd avoid aluminum too. Other than that, they're all pretty good (the reputable mfg.'s) and the only differences will be noticeable when side by side. If I didn't have the Regulator and the Essence, I wouldn't know the difference.
The Sico can has been around forever and lots of people swear by it. TBAC also makes a takedown .22 can and only heard good about it. There's a silencer forum, I forget the name offhand but you can find it easy enough, and that's their gig, comparing cans and what not.