I have shot quite a few of both. I have several barrels chambered in 6 Dasher that I shoot 105 Berger Hybrids in. I have 2 barrels in 22 BR I have shot 88 ELD's in.
The absolute most important thing to know when entering this discussion for PRS shooting is that consistency Trump's all. I had to learn this the hard way while spending money on bullets/dies/barrels to try and Chase the utmost ballistic combination.
Theoretically, the 22 BR 88 ELD combo beats the 6 Dasher in every category except impact energy. I can run the 88 ELD about 100 FPS faster in the 22 BR than I can the 105 Hybrid in the 6 Dasher.
Recoil: This argument ends up not mattering. In my experience, I can see trace often even on the shortest distance shots with the 6 Dasher. The 22 BR has less recoil, but I have already reached the point where less recoil stopped mattering.
Drop: The difference isn't enough to matter. Either you know your drop in all conditions or you don't. No amount of flat shooting cartridge buys you a hit if you don't have your drop figured 100%.
Wind: This is the one every one likes to play the numbers with. I did too. I have found that it also doesn't matter. For PRS you will live and die based on your wind holds and no amount of ballistic advantage makes the difference. I have seen too many people shoot consistently in tough winds at over 1,000 yards with 6 BR's to believe any different at this point. If your wind call is off by 3 MPH at 1,000 yards then it won't matter what cartridge you are using. Consistency again trumps all other factors. It is much more important to have the bullets drift the same amount every shot than it is to have them drift as little as possible.
Splash: In my experience the splash difference is hard to detect. I have shot both bullets a lot and I can see splash from the 88 just as good as from the 105. If the bullet lands in a spot where there isn't much splash signature you are screwed with either choice.
Finally, consistency trump's all. I have found my loads with 105 Hybrids to be more consistent than my loads with 88 ELD's. This is the only thing that matters. Some people surely have found the opposite. PRS was won this last year by a 110 ATIP going 2,775 FPS. It's easy to beat the ballistics of that load. It would be very hard to beat the consistency of that load.