For me, I adjust until 100% consistent lock back, then one more click open for dirty / poor conditions.
As for accuracy, you really "want" everything to go back to the same position consistently. So the less jarring, the better IMO.
As for changing the velocity via a Adj. GB, I'd bet , a average 20 rd box of ammo has a higher ES then any adj. GB could alter velocity.
If a Adj. GB could alter velocities by much.. we would hear about it frequently.
One of the guys on another site, experimented with no gas port ( blocked ) v. normal gas port, on an AR... the difference was not statistically important.