Re: CCW Weapon
Here's some considerations I try to point out when someone brings this up.
1) A hit with a 22 is far more effective than a miss with a 454 Casull, so get something you can easily and comfortable handle.
2) If you DO have to shoot someone, the cops are going to take it from you until the investigation is over and the scumbag's family is almost assuredly going to sue you over it.
3) Since the local LEO is going to take it from you, and once in a while things do get lost in the evidence locker, I carry a CZ-82 chmabered in 9x18 Mak. It's a nice compact pistol, it's military proven, I've fired the crap out of it and had great results, and if you doubt it's potency, read #1. It was $182 including shipping with my CR license.
4) Practice, practice, practice. Practice your draw, practice shooting it, get some snap caps and practice DA pull on the triger, etc.
All that being said, if you want to carry a really potent round, might I suggest a G29? All the snot of a 10mm (which easily outclasses everything you mentioned) and it's the same size as the Walther PPS in 9mm, plus it holds 3 more rounds.
When I have the scratch put together for one, I plan to upgrade the CZ82 to a G29 for my daily carry, but for now I'm not in a big hurry because that little 12+1 capacity 9 is certainly going to do it's job, I have no doubt of that.