For finding what shoot's best in my new rifle: (my own personal system, use or critique as you see fit)
1. I choose a starting charge, from the reloading manual, for the cartridge i'm shooting, the powder I'm using and the bullet weight I choose.
2. I start at the manual's listed lowest charge weight, and work up to the max load in 0.5 grain increments. (I normally wont go over maximum listed charge for listed powder charge and bullet weight)
3. I load 5 rounds at each powder charge weight. Some people load 3 rounds, but to quantify the data on the group size, I shoot 5 rounds with an overall length that's listed in the manual for the cartridge and bullet I'm using.
3. After seeing which powder charge groups the most precise on paper, I then go into optimal seating depth adjustments by using Berger's guidelines here:
Bullet seating depth article I use this method for any bullet type, not just Berger VLD's. The only thing I do differently than the article is; start shooting, with my optimal charge of powder, the furthest "jump" bullet depth first, then work my way closer to the lands/rifling. I don't start shooting jammed bullets first. I shoot them last to be observant of increasing chamber pressures based on how the primer appears when the cartridge is ejected.
I can do all that in about 50-60 rounds.
Then, after all that....If you REALLY want to get into the thick of it for narrower muzzle velocity variations, you do brass prep. Which for me, is: stainless steel media cleaning/tumbling, internal flash hole deburring, trim to length(when needed) and anneal the cases before sizing. You can't do much more than that, besides weighing each piece of brass, weighing each bullet and separating them into weight variance groups and blah blah blah. Weighing brass and bullets and putting them into "weight categories" is overkill and unnecessary, to me. There's only so much you can do to fight your muzzle velocity variation. Brass type(Lapua vs: Hornady vs. Federal etc), brass prep, precision of powder charge weight and seating depth is about as precise as you should be(if you want too) Just keep a log book for each rifle and optimal powder charge and bullet seating depth length to check back on if need be.