No experience with it in a 243, but I used the hsm trophy gold 168gr hunting vld in a 308 to take a nice mulie buck a few years ago. Awesome performance! Perfect broad side shot, 30cal entrance hole, and massive exit hole that I could've put my fist in. Blew part of his heart or lungs through that exit hole. He jumped upon impact, ran about 5-10 yds if that, and slumped over dead. So far I've had great results and accuracy with the HSM/Berger rounds in a 308 and 7rm.