Nothing is wrong with H4350 other than at times it's been rather troublesome to get ahold of at times nd seems to be in limited quantities when it is available. For that reason people have been staritng to veer off to other alternatives. The pro to the Alliant powders is that they are relatively easy to find, work, and achieve higher velocities at lower or equal pressures. In my 22" barrel, I have 147's nearing 2850fps comfortably and in my old 24" upwards of 2900fps. Using Rl16 and the 140's I was about 100fps faster, using less powder than H4350 and still had great brass life with Norma brass.