eh, ide rather use a caliber that will reliably put down an animal fast and clean......not a huge fan of shooting animals with sub-optimal calibers.....or at extreme range (when it can be avoided).......because the risk of wounding the animal increases.........yes there are guys out there that can kill a buffalo with a pellet gun at 900yds........but the problem is EVERYONE thinks they are THAT guy.
personally ide rather use a little too much gun and ruin a little bit of meat if it means giving a clean kill