6.5 Creedmoor will be primary ammo I reload. Might dabble in some .300 blackout. Only other rounds I shoot are 9mm and .223/.556 and those don't appear reloading.
Uuuuhhh, if you shoot 9mm and .223, those calibers are where you'll end up saving the most, assuming you put any value on your time at all.
Again, go to the Dillon web site and find the cost-per-round calculator and the break-even calculator. These will show you the cost per round when you factor in powder, primers, bullets, and brass. Then you can see how long it takes for your cost savings to pay for the equipment you've bought.
BUT: As several have said here, you are quite unlikely to save money because you will shoot more. With that said:
This is where pistol reloading on a progressive press leaps to an early and growing lead in the cost-savings department. I don't pay much attention to "sale" prices for bulk 9mm blaster ammo, but my understanding is $0.16-18 per round ($8-9 per box of 50) is good, and that does NOT include any tax or shipping charges that might be added.
For equivalent reloads, I'm "paying" about $0.11 per round, all tax and shipping included. For top-quality jacketed hollow point rounds (which are the most accurate in my competition pistols, used in the occasional USPSA-style match where the MD throws in a half-IPSC at 100 yards or somesuch), it's about $0.15-17. I NEVER have to pay for 9mm brass because I can pick up buckets of it at the ranges to which I belong. Brass prep consists of pitching it into a tumbler for an hour or two -with a carbide resize die, you do not need to lube the cases. AFTER my rounds are loaded, I run every single one through a Wilson case gauge; those that don't "plonk" easily into the gauge go into the "Glock only" jar. Rationale: my competition pistols have tight chambers which
require external SAAMI-spec sizing. Service pistols like Glock, Sig, etc. are designed to be, above all else,
reliable, so their chambers will easily accept out-of-spec rounds that jam my match guns so tight that I risk breaking extractors to clear them - ask me how I know this. Anyway, repeatedly firing brass in service pistols can expand the case head (solid part of the brass with the extractor groove and primer pocket) fairly quickly, and normal size dies (steel or carbide) will NOT get expanded heads back into spec reliably if at all.
Anyway, once you're set up and rolling with a Dillon 550, you can easily crank out 200 rounds an hour. Yeah, yeah, yeah, the ads say double or triple that rate. Yeah. Read the fine print and see what it takes to achieve that rate. Some people can run a mile in four minutes. So they can honestly say they can run 15 miles PER hour, but they damn sure don't run 15 miles IN an hour. If you want to load crap-tons of ammo faster, you can step up to the 750 or 1050 which are more automated (and expensive), but I've never heard of anyone loading
precision rifle ammo on these. That doesn't mean it isn't done
Loading .223 can be almost as fast except for the case prep (trim, lube, post-reload "un-lube"). Bulk .223 ammo "sale" price seems to be good at about $0.30 per round. Using range brass and bulk 55-grain bullets, my per-round price is half that. I can load precision .223 with the best of match bullets for the same or minimally more than the price of bulk factory ammo (again, assuming I use "free" or heavily-amortized premium brass loaded many times).
For loading precision rifle ammo on a progressive press like the 550, there are plenty of descriptions of how to do that. I use a "hybrid" process with two different tool heads. Not as fast as true progressive reloading, but way faster than a single stage.
More confusion for your decision process! Good luck.
EDIT: The reason I expounded at length on progressive press for pistol/bulk ammo is speed. You can save the same amount per round on a single-stage press but, after you've run the same piece of brass through the single-stage press at least twice and handled it at least three times to get a single finished cartridge, you'll say reloading is NOT worth the cost savings because it takes so bleeping long.