I zero all rifles at their Single-Zero Point (SZP). (the range where only 1 zero would exist...i.e., no hold-UNDERS.)
This equates to ~100y for nearly every centerfire. (this is why (I believe) 100y is the common zero...has nothing to do with being a 'nice round number')
Of note, I do the same with rimfire too. E.g., 22LR w/ match (subs) and 2.5" scope/bore height ~38y.
Using any ballistic engine, enter 100y zero and check for hold-unders (x.x Down, etc.).
Fast cartridges (as well as high scope mounts) might push the SZP out to 120y or so. In that case (as mentioned in above example Kirsch gave), moving your zero out to THAT range would again eliminate your POI ever being ABOVE your POA.
It's not intuitive (for me at least) to have any distance where I'm required to hold under my intended POI.
With a SZP, I know... inside AND outside 100y = some amount of hold-over. Memorize a few points...maybe most likely engagement ranges...or even better, learn what RANGES coincide w/ easy-to-remember mils... e.g., 0.2mil = 170y, 0.4mil = 230y, 0.6mil = 260y...
When I'm headed out with that rifle... "170, 230, 260...170, 230, 260..." and I know that everything inside of 170y (and all the way to 65y...which is approx where most centerfire will also be 0.2mil) is less than 0.2mil...and anything near my SZP (inside or outside) is ~0.0.
Anyways, that's what is simple and intuitive for me.