With good shot placement, just about any bullet will do. However, nature happens. I've used Hornady AMAX's, SST's, round nose soft points, and GMX; Sierra SMK's and Game Kings; Nosler Accubonds, soft points, and BT's; Speer soft points; and probably some other brands/designs. After over 520 deer dropped (we're on nuisance animal permits), I've settled on Barnes TTSX's and use them exclusively on trophy hunts. With a 308, I've had complete pass through's on mule deer, elk, bear and northern whitetails. Best of all, when either nature or I jack up a shot, I can count on the TTSX plowing through anything it hits and exiting the body cavity.