Hey man, you should try to connect with me and my daughter Ashlyn at a match sometime. We shoot a lot of the PRS stuff in eastern WA. We'd be glad to meet your wife and give any assistance that we can.
For some back story, my daughter is 17 but she started shooting PRS matches with me when she was 14. She's phenomenal shooter, beating most of the guys these days. She tied for 4th place at the last Lead Farm match (~80 shooters) and she placed 56th out of ~250 shooters at the PRS national finale and finished #5 Lady in the nation overall last year. She's been top lady in our NW region the last couple years running.
To give some context on rifle weight, she's alwasy shot a full size gun with 26 inch barrel + muzzle brake and a weight of around 18-20lb. Her current rifle is 19lb 4oz with no bipod/mag and 20lb 6oz with bipod. She doesn't use an attached gamer place but just uses a standard full wax canvas game changer with plastic bead fill. While she's pretty strong right now, even at 14 years old she was able to manage the gun.
I think the key is technique when it comes to rifle manipulation. Anytime she is holding the rifle before a stage starts, she holds the rifle vertical barrel up with the buttstock on her right hip and her hand on the grip/trigger. Her hip holds the weight of rifle and she mainly is just hugging it and using her arm/hand to balance it vertically to keep it from tipping over. Her left hand carries and places the game changer first, then her left hand reaches up and grabs the fore-end of the rifle to use both hands to place the gun, either dropping it onto the bag or two hand threading it into a port. She's a pretty fast shooter too, despite this sounding a bit complicated.
Hopefully this description makes some sense. Drop me a PM if you want to connect, I could point you towards some videos on Facebook where you can see her shooting.