I wouldn't do it in an AR-10. I don't think there's anything to be gained. More than that, though, the closing force on the bolt carrier group of an AR-10 is very high, and that introduces an element that is not present with bolt rifles. And I always single-load jammed rounds in a bolt rifle. If you're single-loading, and you release the bolt some before you let it fly, that might make it OK. The real reason I don't recommend it is because it's relatively easy to clean out a bolt action after a round comes apart during extraction of an unfired round. If that happens in the AR-10, there are a lot more places to clean, and they are harder to get to on the firing line.