"In 2022, a 72-year-old man with a history of consuming meat from a CWD-infected deer population presented with rapid-onset confusion and aggression. His friend, who had also eaten venison from the same deer population, recently died of CJD, raising concerns about a potential link between CWD and human prion disease. Despite aggressive symptomatic treatment of seizures and agitation, the patient’s condition deteriorated and he died within a month of initial presentation. The diagnosis was confirmed postmortem as sporadic CJD with homozygous methionine at codon 129 (sCJDMM1). The patient’s history, including a similar case in his social group, suggests a possible novel animal-to-human transmission of CWD. Based on non-human primate and mouse models, cross-species transmission of CJD is plausible. Due to the challenge of distinguishing sCJDMM1 from CWD without detailed prion protein characterization, it is not possible to definitively rule out CWD in these cases. Although causation remains unproven, this cluster emphasizes the need for further investigation into the potential risks of consuming CWD-infected deer and its implications for public health."
"It is not positive to rule out" and "it is not possible to rule in" kind of go hand and hand here.
Couple things are suspect about this article. You're dealing with two elderly gentleman, no mention of vaccination status or other medications, with vague suggestion of eating venison from the "same deer population". (Is that the same state of deer, same county of deer, same herd?) I'd like to know more details on that. The article mentions "aggressive symptomatic treatment of seizures and agitation", which is fine but there's no treatment for any prion-related disease regardless of the cause or source of the prion.
There has been already postulation of the possibility of prion disease related to certain medical therapies to treat certain viruses, or possibly that virus itself. What are the odds that that will be investigated as a potential etiology versus a vague hypothesis to discourage people from being self-sufficient and finding their own food sources?
I'm somewhat concerned that they already have a pre-existing primate to mouse model- mentioned above - have a certain investigators' monkeys accidentally/intentionally released possibly in contact with rodents for unknown transmission for prions? Don't forget the lies and disinformation we were subject to. Lets not forget Fauci's specific directive on "use of fear" to scare people into one behavior vs. another.
They already have been several medications in the category of what is referred to as biologicals, specifically for autoimmune diseases, that have been definitively linked to PMLE, a fatal prion brain infection.
I think it's fair to publish the article, but very premature in the insinuation of the cause and link which is not definitive.
