Shooting Hornady 140 ELDMs, my H4350 load was Hornady case, CCI BR2, 42.5 grains of H4350 giving excellent accuracy and about 2820 fps in a 24" Rock Creek barrel.
My IMR 4451 load was the same bullet, case, and primer, 41.8 grains of IMR 4451 giving about 2700 fps and excellent accuracy.
So...