Safe in my two rifles, ymmv:
Winchester case
72.0 grains Retumbo
CCI 250 primer
130-grain Berger VLD
mv (in my rifles across and Oehler 35P): 3327 fps
This has been my go-to hunting load for several years. Sub-moa in my rifles (Winchester 70 and a NULA M28). This would not be my first choice for elk, as the Berger hunting bullets are a bit soft, but it's excellent for deer and pronghorn. If elk is on the itinerary, try a TSX bullet.