Go to the web site "silencer shop." It will tell you if its compatible or not. But, yes I think it is and you want beable to tell hardly any difference between the 308Win. vs. 300Win. mag, when it comes to sound and the human ear. Now if they say it isn't made for it, then all warranties will be void if you blow it up. But, a lot of people use suppressors on larger guns than what its made for, """ Only If The Barrel Is Of A Certain Length!!!!" If a barrel is long enough, the pressures will hit the baffle with less "sudden impact," will call it. People say pressure, but if you think about it, where would the pressure go? How would it decrease if it can't escape? It may just be more evenly dispersed, in stead of so traumatic, if you think about it. "I would really like to know myself."