Of course. Think about it. As soon as the bullet leaves the barrel, it starts to fall. Imagine that the barrel is pointing directly at the bull and there is a line of sight running through the barrel center to the target. When fired the bullet will drop below that line and your shot will impact low or off the target. In order to cure that little problem, you point the barrel up a little. That imaginary line down the center of the barrel is pointed higher on the target or even above the backer. When fired, the bullet starts to drop below that center line. But since the line was pointing above the target, the bullet rises and then "falls" into the bullseye. There is another line running through the center of your scope to the bullseye, call it an eye-line. Depending on range and geometry, the bullet will probably rise through that eye-line then drop right into the spot where the eye-line intersects the bullseye. The point where the bullet rises through the eye-line is the crossover.
Take your weapon to a place where you can shoot beyond 300 yards. Get a 300 or 400 yard zero. Prop the gun on sandbags remove the bolt, put the scope crosshairs exactly on the bullseye. Without disturbing the gun, look through the barrel. The barrel centerline will be a couple feet above the bull. My 300WM has a 200 yard zero. My 500 yard zero is about 8 MOA above the 200 yard zero -- 8 MOA at 500 yards is a little over 40 inches higher than 200. My 1,000 yard zero is up 28 1/4 MOA, about 280 inches, or about 23 feet above the target.
