Targets under 2 moa and targets over 800 yards are the exception in PRS- though you will see both. Proned out, with a solid bipod and a good rear bag, the target presentations are all shootable.
The real challenges in PRS are the props. Shooting from a chain suspended between 2 posts. Shooting from the “latch end” of an open aluminum gate. Shooting from a slick 45deg ledge. Shooting from a prop that collapses when pushed or pulled.
Guys/ladies at the top are not shooting the ultimate flat shooting laser beam wonder cartridge. They are shooting some flavor of short action 6mm. A br, bra, dasher, etc. There are “higher performance” cartridges, but at the very top everyone can make the hits. The name of the game in the rarified air of the top shooters is self-spotting misses and correcting.
You are not going to approach the low recoil of a 20+ lb 6mm bra with any AR-10. This puts you behind the 8 ball with setting up your position- which will be a compromise because of the time limit and stage design.
Can you go out with an ar-10/sr-25 (or variant) rifle and compete for high overall score at the national level in PRS? History suggests ‘no.’ Can you go out with an large frame semi auto and shoot a match, surprise yourself, disgust yourself, learn about your ‘system,’ and have an enjoyable day turning money into noise with a bunch of fellow shooters? Yes. Yes you can.