You could get almost any ammo out there "dead nuts" on at 200 and 300 without using any sort of calculation at all. Dial .5 mils for the former, 1 mils for the latter and you might very well be within the margin of error of most shooters (e.g. if you're a 1/0th mrad off, that's about an inch... and if you're shooting a two inch group, you might never see it). That might vary a touch depending on the bullet and the starting MV. Point being, if you use any system and it evidences error at 200 or 300, something is very wrong.
If you peruse this sight, you'll see any number of folks that have meticulously entered every scrap of data to be had on the projectile looking to "true" their calculations or griping that their chosen software isn't matching up. The general school of thought is true to velocity at 600 based on your DOPE (i.e. fiddle with MV until the output matches the observation... shoot it first), and then true via BC at distance. It's been discussed here on the Hide extensively.
The advantage of weaponized math is that it's built on your DOPE - hard data - not a theoretical model that needs to be tweaked. In fact, in generates the data you can go back and tweak the model with. Win - win. ;-) The "disadvantage" is that you actually have to shoot - torturous!