Best factory ammo for AR10 Target AND Hunting?

Factory rifle or a home built?
Bbl length?
Gas system length?
Trigger?
Buffer weight?
Suppressed or unsuppressed?

130 AR Hybrid is going to be hard bullet to beat.
 
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Thin skinned medium game at close to moderate range? Buy a box of everything you can find locally. Leave any FMJ on the shelf. Shoot groups. Decide what shoots best. Buy a lot of that. Don't sweat bullet construction too much. Put them where they count...
 
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Each barrel is somewhat different...you'll have to play around a little...that said...M118LR does better for me in shorter barrel semis (under 18") than 168 FGMM...
 
Barnes 127 LRX, Hornady Precision hunter, Federal premium 130 Berger AR hybrid all shoot well with needing to adjust zero in mine. I bought a box each of several different flavors to see how they shot. Still have a box of Hornady GMX 130’s to try.
 
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Plain old Remington 150 core-lock, Hornady Black (168 amax) , Hornady 178 ELDX precision hunter all shot good out of my LMT. MOA or better, usually.

I use the core-lock for pig if I’m specifically hunting them as I tend to blast them while walking about in the farm. And I’ll fire a bunch of rounds until I see no more running animals.

However, the Hornady has way less POI deviation than the Remington in my particular weapon when I go from unsuppressed to suppressed.

As stated, you have to experiment to see what your toy prefers.
 
I would recommend:

- Federal Gold Medal 175gr Sierra Matchking
- Hornady TAP Precision 168gr BTHP
- Hornady TAP Precision 168gr A-Max
- Black Hills Gold 168gr Barnes TSX

For practice, look at the Prvi Partizan M80 .308. It's all NATO spec.

Good site for this stuff is Palmetto State Armory.