Nucleus has an 80deg bolt lift, customisable striker springs (comes with 25lbs and can go as low as 16lbs ie 40% lighter), has a normal push button bolt stop like any other Remington clone action (it’s just on the other side and stronger), has a bayonet style bolt shroud just like the bighorn (ie no tools and even if you decide to use a hex screw driver it takes an extra 5 seconds), is smoother and binds less than a bighorn (three lug with three anti bind rails) and swapping the bolt head/measuring to the lands distance is even easier and simpler because there is no crush washer.
Nucleus has a ton of features and no downsides, it just has a different personality and depends on if you prefer the two lug 90deg Remington clone feel or you’re happy to try something new and different.