I run .308 brakes on ALL of my rifles, .223, 6mm, 6.5mm, .284 and .308. Testing by Cal Zant of Precision Rifle Blog fame, has shown that loss in performance of an oversized brake on smaller calibers is only 2-3%. I like the convenience of having/using a couple of brakes like the APA Gen 2s on multiple rifles, or when changing barrels, regardless of caliber.