I can't speak about the ES/SD of handloads yet, as I'm just beginning the reloading process myself. However, I have used a variety of different commercial loads in F-T/R competitions at ranges from 300 to 1000 yd. Most factory match ammo such as FGMM 175s, Black Hills 175s, CorBon 175s, etc., will give you ES values in the neighborhood of 35-50 fps, sometimes a little more. The SDs will run from around 10 to the low teens. The ammunition I have used with the best results in competition is the Applied Ballistics 175 gr Tactical load. Because the charges in it are individually weighed, along with the higher BC 175 gr Berger Tactical bullet and generally much more care put into it's preparation, it routinely gives me ES numbers in the low to mid teens and SDs below 10. This load is running between 2750-2760 fps from a 30" barrel. As long as I don't do anything stupid behind the rifle, this load has worked very well out to 1000 yd. In contrast, I shot FGMM 175s at our last 1000 yd match at Camp Pendleton (elev. ~ 420 ft). This load also runs just above 2750 fps out of the same rifle. The wind conditions were pretty challenging with rapidly shifting headwinds from 10:00 to 2:00 at about 13-16 mph, with gusts over 20; however, I've shot the AB175 load under similar conditions plenty of times and done reasonably well. With the FGMM 175s, it was a bloodbath. Many 8's high and low, just all over the place vertical. Although I'm sure the wind had something to do with that, I also believe the load was a big factor. At 2750 fps, the SMK 175 is going just under Mach 1.1 at 1000 yd. When you add in the 50 fps ES, it just isn't a recipe for success. Unfortunately, it was all I had, so I used it. The tighter you can get your ES/SD values, the better off you will be. As XTR mentioned, you can probably get the speed up a little as well by using somewhere in the range of a grain more Varget (as long as it's SAFE in your setup!). 44.5 gr of Varget pushing an SMK 175 has been known to be a pretty good performer for quite some time. Good luck with it.