Has anybody tried h100v in 243 or 243 ackley yet

Yes I have, I did find better accuracy with others.
But that is my gun not yours. You very well may have a rifle that likes it.
If you live near me (central WA) I have half a lb you can have and try.
 
Played around with it for awhile last year in my Win model 70 coyote light .243. It gave really promising results out to about 300yds and from there it fell apart. My last load was 39.6gr / 87gr Vmax / .050 jump at 3007 fps.
 
I've tried it in both .243 and a fast twist .22-250. I never could get my ES and SD numbers down. I found other powders easier to tune than H100V; However, H100V gave some great velocity.
 
I don't think I changed the powder load at all if I did it was minimal. I just remember switching to cci 450s and my sd's droped and became very consistent.