I did a test earlier this year with my .260, I shot 5 with the brake off, 5 with a 419, 5 with a Brad's precision, and 5 with a slabbed Muscle brake. The results where dramatically different and it wasn't only POI. For whatever reason the muscle brake had the tightest group - around .3. the Brad's was tight but had a bit of vertical and was right at the half inch mark. With no brake on it was almost a perfect half inch circle (meaning vertical and horizontal dispersion was the same). And lastly the 419 was nearly an inch in vertical. Thinking something was weird I used degreaser and made sure the brake was clean and torqued well, tried it again and the same thing happened with the 419.
Now they all shot the same load, I'm sure if you worked up a load for each they would end up just as accurate as another. Hope this helps you.