IMR 4064 & .308 = who cares what the charge weight is, as long as it is safe.
Seriously though, what bullet are you shooting? 42-43 grains will probably work for just about any bullet (150-185 grain bullet), pick a weight and go shoot. There is an old thread on here about 4064 being used for FGMM and also for the military using 41.75 grains with the 175 smk. The 168 SMK FGMM load was 42.8 grains, I think.
I did a lot of testing with this powder and these two bullets about ten years ago and basically found the powder so well suited for the caliber, charge weight didn't make much difference, if any.
Fast forward to today, I've adopted
@Feniks Technologies approach to reloading. For example, in 6BR, I did zero load development with a new powder/bullet combination. Instead I loaded up 30 grains of VVN540 behind a 109 Berger, and the results were incredible at distance and up close. Last range trip, I made consecutive first round hits at 550 on an 8", 5", 3", & 1.5" plate.
His and
@Ledzep findings has lead me to rethink the entire reloading concept. This was a difficult pill to swallow after so many years of thinking differently, but the results seem to speak for themselves. And I don't waste time and mental energy with ladder testing/OCW/etc.