MK II or MK III or 22/45 are all going to be very similar. I recommend you get a Volquartsen extractor if reliability is your goal.
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It really depends on the level of competition you're wanting to participate in. For plinking and competition where a caliper won't be used for measuring the results, I recommend a Ruger MKII or MKIII. Unlike the Browning Buckmark, which I also like, no screws are needed for disassembly, and no replacement washers and buffers are ever needed. If you're serious about competing, then you may want to get one with a premium barrel (Clark, Volquartsen), which may adversely affect reliability with any ammo (or require that you stick to a specific type of ammo), or a more advanced, and expensive, design, usually meant to be used with a very specific type, weight, and/or velocity ammo. I own or have owned many makes, but the Rugers are the ones that are shot the most, informally, because they're the most reliable.
I think you might need a model 41 that has not had an idjet's dick skinners in it.