I am no fan of Apoquel. Our pup has had issues his entire life, around the pads of his feet red, eyes watering scratching holes in himself. He was on apoquel for a while and his bones started to just....go away. Vet wanted to take his front left leg. Wife was really upset about it so she started looking. Turns out in some cases apoquel will cause bone mass to start to go away. Took him off of it and in two months his Xrays are much better. The stuck him with a needle and took a bone sample and sure enough it was growing back. Vet had never seen it before, and she is a good vet IMHO.
I am not sure what he is on now, I would have to look. He has a cream for his "arm pits" and other raw spots.
I know in the shelter it is a pretty big issue. Plan on doing more there once I retire in roughly 10 months.