Seems like max effective range with the extremely heavy and high BC .416 and .375 and even .50 bullets would be extremely far even when loaded to subsonic levels. Has anyone yet built a rifle and cartridge that was purpose built for this? Given the large bore diameter and decreased powder volume, it could be a very short barrel to achieve max subsonic velocities. You could also design the case by necking up a much smaller cartridge since powder volume would be much less. It would be light, extremely portable, and with a suppressor very very stealthy. For military use, the ammo would still be small enough to be practical for carrying high volume and I an imagine the kind of havoc such a weapon would wreak upon the enemy.