A couple points on DOT #s and CDL requirements. First, commercial over 10k GVWR needs a DOT # and annual inspections, but private use does not. Trucks with over 26k GVWR used commercially needs a Class B CDL, and Class A CDL with a 10k trailer behind it. Commercial trailers rated over 10k needs DOT inspections as well.
If you buy your truck through your company/LLC/other commercial entity, guess what, you have a commercial motor vehicle and have to abide by all FMCSA regulations. Unless you spec a 350/3500 at 10k GVWR, you need a DOT #, and I have no idea why anyone would buy that much truck and do that. Farms in most states are excluded from many of the regs, but have to have farm plates and are restricted in how far from the farm those exemptions apply, and the exemptions typically don’t go over state lines. Local farmers know their regs where they do apply though.
Like TxWelder35 said, FMCSA has zero to do with personal vehicles. It is strictly commercial use only.
Personal vehicles, your state will be the ruling entity as far as license requirements, but traveling interstate can get you into a hassle with weights and lengths, as well as running doubles. Some states require specialty endorsements on your license, but interstate if your license is good for your state, it's good for traveling cross country. Here's a good chart for what is required where for heavy/long RV hauling.
Here's ALL you need to know about what driving licenses you need for each RV type.
www.godownsize.com
I’ll stay out of the rest of the conversation because the only diesels I run say Freightliner on the front. I’d personally pick whichever gave me the best bottom line price. All present day diesels are having maintenance issues with the Obama piss and smog regulations on them. Deletes aren't a real solution for most of those issues as well as running you into issues with other regs, especially considering there is going to be a ton more regulation enforcement on that happening in the next four years.