After testing weight sorted Federal Champion 22LR LRN and finding that they produced 60% smaller groups than non weight-sorted cartridges, I decided to test the other big old-school 22LR accuracy technique: sorting cartridges by rim thickness.
The thickness of the a 22LR rim can effect the amount of headspace of the bullet in the chamber. And presumably, the thickness could also effect the amount and burn rate of the primer inside it.
Your milage may vary.