I recently start to make some handloads for my in laws 22-250. It's a New England break open single shot. When shot with factory ammo everything works fine, but when we shoot the handloads I made it come opens after firing almost every round. Is this something as simple as the sizing of the case? All brass was full length sized when I got it. Using Winchester brass, Nosler 55 grain bullets, and Varget powder. I have gone from low to high end of the powder so I don't think that is the problem. Thanks for any help.