Re: What 45 to buy????
I carried a Sig P220 Equinox for the last five years, in SC and ST. That being said, I have the benefit of a large frame (6'3" 220lbs). Had no issues through out its use, and only noticed minimal holster wear using a kydex Comptac CTAC. Offset it with a spare magazine holster on the off hand side, and an ankle rig that held an additional mag.
When I was making the decision, I went through every 45 on the market at the time that I could get my hands on. I chose it over the rest because it 'fit' my grip the best and synched with muscle memory rapidly. From a natural position, a Glock always seems to be canted downward. The 1911s just felt overly complicated.
All that being said, I feel obliged to echo others in the following: Gun, Gear, ammo, and more ammo. I was fortunate enough to find a range that would allow you to perform defensive shooting routines.