I suppose it depends what you want to do with it. Do you want to hunt with it and maximize your Point Blank Range or do you want to compete with it? The 20 MOA base doesn’t really have anything to do with it other than to add to the amount of elevation you have left to dial. Most competitive shooters will zero at 100 yards because there are less atmospheric factors in play at that distance. Humidity, temperature, altitude, and wind don’t matter as much at that distance. Plus, once zeroed at 100, all their holds will be hold overs with no hold unders.