So I just bought the new Ruger RPR 338 LM it comes with a 30 MOA rail and my SPUHR mount that I already had my S&B 5-25 in has 20 MOA built into it so that's 50 MOA of cant. I didn't think I would have a enough down elevation left to get a 100yd zero, but I got lucky and I was able to zero it at 100yds with I think very little left maybe 2-3 clicks. I ended up with 26 MILS of up elevation which I think is around 2200yds for the 338 LM. I will mostly be shooting it around 600-1000yds and occasionally 1760 yds. Anyway just wanted to share my experience sometimes you don't know until you try.