Just went through a similar, but opposite situation. Was using 175 SMK's from a 1/10 twist and it did well. Bought a new gun in 1/12 twist. No matter what speed, seating depth etc. we used a heavy, it would not shoot.
Went to a 155 scenar around 3,000 FPS in the 1/12 twist, it's shot the best it ever has.
Now if you have a 24" Savage 1/10 twist. I've shot 1,100 yards with a 24" 1/10 using a 175 SMK, Win brass and 44.0g Varget, if I recall around 2,700. You would need to check how much jump you need. Mine liked around .020-.030".
Back off on the amount of 4064 and maybe start somewhere around 42.5.