Here's what I do:
Dan Newberry's OCW. I usually start .015 off the lands. I also use Quickload as well, so I don't have to run the entire gamut of charges, I pretty much know where I want to be, so its either 5 or 6 charge weights, 3 shots each, in .3 increments. I find the middle node of consistent poi.
Seating depth test @ 300-500 yards - test between .005 off lands to .025. I don't like jamming. 95% of the time seems to be between .015 to .020 off lands where I end up.
Go back and go down .1 grains, same charge from step 1, and up .1 grains. (so if your OCW is 42.5, test 42.4, 42.5, & 42.6) Run at least 6-7 shots per charge over chronograph and choose smallest ES/SD. You would think these small differences wouldn't make a difference, but in some cases, I've seen quite a variation.
Gets me a solid load in roughly 50 shots. You can even take it further and run seating depth tests in smaller increments.