First, the Cadex chassis is first class. Yes, I am a Cadex dealer, but we also sell AI and some McMillan. If you are looking for a basic platform, McMillan and AI have some great options. I use AI for building Mk13 Navy/Marine sniper rifles. Cadex, however, is a generation ahead in the design and engineering. Lug design and roller bedding is fantastic. Cadex owns the large bore space. Anything above .338 fits better, in my opinion in a Cadex chassis.
Now, to your question. The Dual Strike is the foundation platform. This is a big chassis, and has lots of rail space committed for tactical use. The Dual Strike is a must for big bore. The Dual Strike has a bigger tube, so it will accommodate very thick barrels. The Lite Comp is probably the most popular chassis that I sell. It is great for most rifles, especially .308, 6.5, .260. The tipping point is at .338, where either chassis is good. The comp lite does not have the rails that the dual strike does. If you are mounting a dedicated scope and shooting at the range, then the lite comp is probably right for you. If you are out in the field, and need mounting space on your rifle, or changing scopes, the Dual Strike is a workhorse and will not disappoint you.
Personally, I am a big fan of the Dual Strike and Lite Strike, but I am a tactical guy.
Hope this helps. Give me a call to talk you through some comparisons.