I've been using a Dillon 650 for the last twenty years. It worked perfectly the first time I set it up and has worked without a hitch since. I have tool heads set up for a few cartridges which is quite convenient.
A few notes. The powder thrower doesn't throw coarse stick powders that well, so don't expect 0.1 gr accuracy with stick powders. No powder thrower I know of will. On the other hand you can get a powder funnel die and use a Chargemaster or similar to get accurate powder throws. There are those who say the stock tool heads leave a little runout with rifle cartridges but there are aftermarket tool heads (Whidden?) that are supposed to be better. I've never tried one.
Finally Dillon's No BS guarantee, they aren't kidding. One guy had his house burn down and Dillon replaced his press free of charge.
Is it good enough for PRS? Well, some highpower shooters reload on a Dillon so I suppose so.