well a few things.
1) all ham radios are essentially 2 way walkie-talkies......its just a matter of finding the right frequency ( more on this in a minute)
2) yes, hand held units are "worth it".....depending on what you want from them.
if you buy a decent radio, and more importantly a GOOD antenna....you should have no problem transmitting 50+ miles depending on terrain........and thats the kicker.....terrain.
ham radios operate on "line of sight".....meaning if you are in a dense forest, in a city, or in a valley trying to communicate with someone on a mountain top....you are going to have a lot of trouble. we have ways around this....but they arent like cell phones.
the benefit to them is you have access to ARES/RACES bands...most police and emergency bands....NOAA weather bands.....plus access to GMRS/FRS bands ( although not 100% legally)
going back to point 1....yes, you can use a ham radio to talk to "blister pack radios".
blister pack radio operate on the GMRS/ FRS bands....essentially those are a block of radio frequencies uncle sugar desginated for use with general "family" radios and dont require a license.....there are a few requirements for radios that operate on these bands (power and antenna requirements)......but thats about it.
now the reason its an issue is because nearly all HAM radios have removable antennas ( a no-no for FRS) and operate at 4+ watts (also a no-no for FRS)
many HAM radios also restrict those bands and wont permit transmission (there are mods for this as well)......but just sometihng to keep in mind.
but assuming you have a radio that will dial to a FRS/GMRS frequency....you can talk on it like a regular walkie talkie.
now if you go on the HAM forums and ask that question....all the poindexters are going to bawk and moan and cite FCC law and threaten you with prison time.........but none of them will even point to a real world example of where the FCC went after someone violating that law.
the general consensus is, unless you are actively causing trouble.....jamming bands and such, they are not really going to be bothered with you.
all in all, think of a ham radio as essentially a regular walkie talkie with a little more power, and slightly more control over what radio frequency you dial too.....they are really nothing special.