I am most certainly in the camp that you should shoot what you like and are comfortable with. Heck, we have local down here that occasionally shows up and shoots matches with his 300WM. And yes, it does take a toll on the steel at the shorter distances And no, he’s not competing at the top level even though he is a good shot.PRS and my 6.5PRC RPR are new to me, but I fire my Barrett M82A1 .50 BMG regularly, so I don't think recoil is going to be an issue (if that's what you mean.)
The thing is, there are too many stages that require 10 shots or more in 90 seconds on close in steel or varying ranges. No matter how well you handle recoil nor how good your fundamentals are, you will be challenged to keep up with those shooting 6mm rounds over 30-35 grains of powder.
Just sayin’...