Re: new bolt gun for wife
I'll chime in if you haven't already bought the gun.
The .223 is a fine cartridge and easy to shoot, but at longer ranges can be difficult to master.
You need to verify that SPS has a 1-9 twist. The tactical does for certain, but a varmint model will most likely have a 1-12, limiting you to 55 grain bullets.
The .243 is an awesome cartridge, louder, still light on recoil and far easier to shoot at extended ranges. It eats barrels though and match ammo is almost strictly a handloading proposition. There is match ammo out there, but it is expensive. Luckily, there is plenty of highly accurate hunting ammo available.
You haven't said if there was a price limit on the rifle.
My answer:
Savage LRP in 6.5 CM. Excellent accuracy, long barrel life, light recoil and comes in an excellent stock (the SPS stock sucks and will need replaced, adding at least 230 dollars more to the cost).
It is a win-win all the way around. Don't handicap your wife with a cartridge that is very challenging to shoot beyond 200 yards accurately.