In my opinion, and the empirical data tends to support this, somewhere around 338 Lapua and above, a suppressor is inferior enough to a good break that there is a perceptible increase in recoil with the suppressor compared to an efficient muzzle break. When you get up to 50 caliber, it is very noticeable. And 50 caliber is hard enough to shoot effectively at baseline even with a good break.
This is why I removed my elite iron 375 can and break from my 375 Chattah and now I just shoot it with a terminator T5 muzzle brake
From now on, I am never going to shoot anything above 338 suppressed unless it has an anchor break on it like the new thunder beast Magnus cans
If you have the opportunity, screw that brake on hand tight and shoot a shot and take a video and then unscrew it and screw on the 50 caliber can and take a video or better yet post a video of the whole thing in sequence so that we can seethe movement of the rifle under both conditions