Louisiana. Probably a toss up between the Timber Rattler and the Cotton Mouth. Though I must say the Black Bear is making a comeback. Of course, tick and mosquito spread diseases are always present. And though verified attacks in our state are practically non-existent, Alligators have been seen as large as 13 feet.
But the critter making the biggest mess of human beings is the RED BUG. So tiny they are microscopic, but the welts they leave on a fellow look more like when he is being hit with 105 howitzer round.