what type of difference would I see in brass

I would skip the Nosler brass. It's too soft. I have played around with Nosler brass in a couple of different calibers and the brass was toast after a couple of firings. Get the Prime once fired. It's a great deal at usually 50 cents per once fired and they can take a heavy load.
 
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I would skip the Nosler brass. It's too soft. I have played around with Nosler brass in a couple of different calibers and the brass was toast after a couple of firings. Get the Prime once fired. It's a great deal at usually 50 cents per once fired and they can take a heavy load.
I have 6-7 reloads each so far on my Prime .260 brass and my rifle likes it just fine. I found them to be very consistent in weight and I like the fact that they have thin necks, even if it does mean I have to use a collet die after full-length sizing. I get consistent MV and low SDs. So far, I've used 200 pieces and am prepping an additional 200 for it's first hand loading.