Not really. AA4064 was made to compete with IMRs version (before they were owned by the same folks). AA4064's burn rate is slightly slower and as stated before, folks find they need more of it to match IMR4064 velocities. Most folks found they also had pressure signs with AA when they did not with IMR. As also previously stated, work up charges when switching powders. You should even do so when switching LOTS of the same powder.Is accurate 4064 interchangeable with IMR?