Anything that can safely burn E10 (just about any passenger vehicle from the past quarter h century) can also burn E15 if in proper working order. I mean, if you're right on the edge of a failure in the fuel system or something else is grossly out-of-wack (dirty MAF sensor, etc.) then it might be an issue, but the difference in stoichiometric air-fuel ratio just isn't that significant with an extra 5% ethanol. You will see a mileage hit in vehicles that don't have aggressive enough timing calibration to take advantage of the extra corn, and that sucks. But nothing should get hurt.
The stuff to worry about is the various trash that wasn't designed to burn E10 (sorry, but anything marketed in the US in the past 20 years should have been designed for this reality). That equipment will simply degrade faster with E15, which is obviously not good.